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Hematology, Oncology & Immunology

Allergy & anaphylactic shock

Anaphylaxis is a severe, life-threatening allergic reaction that requires immediate intervention. Recognizing and diagnosing anaphylaxis quickly is crucial for effective management. The primary treatment involves the prompt administration of adrenaline (epinephrine), supported by adjunctive therapies like antihistamines and corticosteroids. Proper patient positioning and airway management are essential, with special considerations for populations such as children and pregnant women.

Drug allergies are a significant concern in clinical practice, impacting treatment options and patient safety. Accurate diagnosis through skin testing and in vitro tests is vital for managing these allergies effectively. Updated guidelines provide evidence-based strategies for common drug allergies, including penicillin, and highlight the role of desensitization and alternative therapies. Special considerations for populations like children and pregnant women ensure tailored and safe treatment approaches.


Anaphylaxis

Guideline

Anaphylaxis

Emergency treatment of anaphylaxis: concise clinical guidance

Andrew F Whyte et al., Clinical Medicine (2022)

What’s inside

This article provides concise clinical guidance on the emergency treatment of anaphylaxis, focusing on immediate interventions and management strategies.

Why it’s relevant

Anaphylaxis is a life-threatening allergic reaction that requires prompt and effective treatment. Clear guidance is essential for healthcare professionals to manage this emergency effectively.

Key focus

  • Recognition and diagnosis of anaphylaxis
  • Immediate management strategies, including the administration of adrenaline (epinephrine)
  • Role of adjunctive therapies, such as antihistamines and corticosteroids
  • Importance of patient positioning and airway management
  • Considerations for special populations, such as children and pregnant women

Takeaway

The article emphasizes the importance of rapid and appropriate intervention in managing anaphylaxis, providing clear guidelines to improve patient outcomes in emergency settings.


Allergy

Review

Drug allergy

Drug allergy: A 2022 practice parameter update

David A. Khan et al., Journal of Allergy and Clinical Immunology (2022)

What’s inside

This article provides an updated practice parameter for the diagnosis and management of drug allergies, reflecting the latest research and clinical guidelines.

Why it’s relevant

Drug allergies are a significant concern in clinical practice, impacting treatment options and patient safety. Updated guidelines help healthcare professionals manage these allergies effectively.

Key focus

  • Updated definitions and classifications of drug allergies
  • Diagnostic approaches, including skin testing and in vitro tests
  • Management strategies for common drug allergies, such as penicillin and other antibiotics
  • Role of desensitization and alternative therapies
  • Considerations for special populations, including children and pregnant women

Takeaway

The article offers comprehensive, evidence-based guidelines for diagnosing and managing drug allergies, emphasizing the importance of accurate diagnosis and tailored treatment strategies to improve patient care.

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